Many of you will be wondering exactly where the recently released Metroid Prime 4 fits in the series timeline and thankfully Nintendo has told Famitsu the answer. Metroid Prime 4 is set after Super Metroid and before Metroid Fusion. Due to Samus ending up in another dimension in Metroid Prime 4, Nintendo says it “wanted to be able to create a free and original setting for Metroid Prime without affecting the 2D Metroid series.”
Thanks to Greatsong1 for sending in the news tip!

Rip metroid series. flop game
Stay off drugs.
Thanks for your opinion.
Just give me Metroid Prime 2 Remaster. Mich better game.
It seems like they do care about the lore after all. What about the Mario franchise?